7Y42
Cryo-EM structure of the SARS-CoV-2 spike glycoprotein in complex with all-trans retinoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, D) | Spike glycoprotein | polymer | 1121 | 124168.5 | 3 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 2 | AA, BA, CA, D, DA... (D, A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 27 | Chemie (NAG) | |||
| 3 | GA, M, W (D, A, B) | RETINOIC ACID | non-polymer | 300.4 | 3 | Chemie (REA) |
Sequence modifications
A, B, D: 27 - 1147 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Phe 166 | Cys 166 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 372505.5 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 6873.9 | |
| All* | Total formula weight | 379379.4 |
