7XC4
Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin
Summary for 7XC4
Entry DOI | 10.2210/pdb7xc4/pdb |
Descriptor | Papain-like protease nsp3, 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid (3 entities in total) |
Functional Keywords | g-quadruplex-binding, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 29419.67 |
Authors | |
Primary citation | Li, J.,Zhong, F.,Li, M.,Liu, Y.,Wang, L.,Liu, M.,Li, F.,Zhang, J.,Wu, J.,Shi, Y.,Zhang, Z.,Tu, X.,Ruan, K.,Gao, J. Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen. J.Med.Chem., 65:15227-15237, 2022 Cited by PubMed: 36356292DOI: 10.1021/acs.jmedchem.2c01168 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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