7XC4
Crystal structure of SARS-CoV-2 NSP3 Macrodomain 3 (SARS-unique domain-M) in complex with Oxaprozin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Papain-like protease nsp3 | polymer | 129 | 14416.5 | 2 | UniProt (P0DTC1) Pfam (PF11633) UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3,nsp3 |
| 2 | C, D (A, B) | 3-(4,5-diphenyl-1,3-oxazol-2-yl)propanoic acid | non-polymer | 293.3 | 2 | Chemie (BJ6) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 212 | Chemie (HOH) |
Sequence modifications
A, B: 551 - 675 (UniProt: P0DTC1)
| PDB | External Database | Details |
|---|---|---|
| Phe 547 | - | expression tag |
| Gln 548 | - | expression tag |
| His 549 | - | expression tag |
| Met 550 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28833.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 586.6 | |
| All* | Total formula weight | 29419.7 |
