7WYS
Crystal structures of Na+,K+-ATPase in complex with istaroxime
Replaces: 7EVXReplaces: 6KPYReplaces: 7DDGSummary for 7WYS
Entry DOI | 10.2210/pdb7wys/pdb |
Related | 7D91 7D92 7D93 7D94 7DDF 7DDH 7DDI 7DDJ 7DDK 7DDL |
Descriptor | Sodium/potassium-transporting ATPase subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose, Sodium/potassium-transporting ATPase subunit beta-1, ... (11 entities in total) |
Functional Keywords | na+, k+-atpase, membrane protein, ion transport, cardiotonic steroids |
Biological source | Sus scrofa (pig) More |
Total number of polymer chains | 6 |
Total formula weight | 322600.26 |
Authors | Ogawa, H.,Cornelius, F.,Kanai, R.,Motoyama, K.,Vilsen, B.,Toyoshima, C. (deposition date: 2022-02-16, release date: 2022-05-04, Last modification date: 2023-11-29) |
Primary citation | Kanai, R.,Cornelius, F.,Vilsen, B.,Toyoshima, C. Cryoelectron microscopy of Na + ,K + -ATPase in the two E2P states with and without cardiotonic steroids. Proc.Natl.Acad.Sci.USA, 119:e2123226119-e2123226119, 2022 Cited by PubMed: 35380894DOI: 10.1073/pnas.2123226119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.71 Å) |
Structure validation
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