7WPN
Methionyl-tRNA synthetase from Staphylococcus aureus complexed with a phenylbenzimidazole inhibitor and ATP
Summary for 7WPN
Entry DOI | 10.2210/pdb7wpn/pdb |
Descriptor | Methionine--tRNA ligase, ADENOSINE-5'-TRIPHOSPHATE, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | ligase-inhibitor complex, ligase/inhibitor |
Biological source | Staphylococcus aureus subsp. aureus COL (Staphylococcus aureus COL) |
Total number of polymer chains | 1 |
Total formula weight | 62392.80 |
Authors | |
Primary citation | Yi, J.,Cai, Z.,Qiu, H.,Lu, F.,Luo, Z.,Chen, B.,Gu, Q.,Xu, J.,Zhou, H. Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic Acids Res., 50:4755-4768, 2022 Cited by PubMed: 35474479DOI: 10.1093/nar/gkac285 PDB entries with the same primary citation |
Experimental method |
Structure validation
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