7W3Z
Cryo-EM Structure of Human Gastrin Releasing Peptide Receptor in complex with the agonist Gastrin Releasing Peptide and Gq heterotrimers
Summary for 7W3Z
Entry DOI | 10.2210/pdb7w3z/pdb |
EMDB information | 32297 |
Descriptor | Maltodextrin-binding protein,Gastrin-releasing peptide receptor, Gastrin Releasing Peptide PRGNHWAVGHLM(NH2), Guanine nucleotide-binding protein G(q) subunit alpha, ... (6 entities in total) |
Functional Keywords | gpcr, gastrin releasing peptide receptor, membrane protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 6 |
Total formula weight | 225530.88 |
Authors | |
Primary citation | Peng, S.,Zhan, Y.,Zhang, D.,Ren, L.,Chen, A.,Chen, Z.F.,Zhang, H. Structures of human gastrin-releasing peptide receptors bound to antagonist and agonist for cancer and itch therapy. Proc.Natl.Acad.Sci.USA, 120:e2216230120-e2216230120, 2023 Cited by PubMed: 36724251DOI: 10.1073/pnas.2216230120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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