7W2C
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084
Summary for 7W2C
Entry DOI | 10.2210/pdb7w2c/pdb |
Descriptor | Sigma non-opioid intracellular receptor 1, GOLD ION, 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, ... (5 entities in total) |
Functional Keywords | sigma receptor, membrane receptor, s1r, ligand entry, membrane protein |
Biological source | Xenopus laevis (African clawed frog) |
Total number of polymer chains | 12 |
Total formula weight | 310873.58 |
Authors | |
Primary citation | Meng, F.,Xiao, Y.,Ji, Y.,Sun, Z.,Zhou, X. An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway. Nat Commun, 13:1267-1267, 2022 Cited by PubMed: 35273182DOI: 10.1038/s41467-022-28946-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.335 Å) |
Structure validation
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