7W2C
The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, C, E, B, D...) | Sigma non-opioid intracellular receptor 1 | polymer | 225 | 25121.7 | 12 | UniProt (Q6DCU6) Pfam (PF04622) | Xenopus laevis (African clawed frog) | Sigma 1-type opioid receptor,Sigma1-receptor,Sigma1R |
| 2 | AA, DA, EA, GA, HA... (D, F, G, H, A...) | GOLD ION | non-polymer | 197.0 | 24 | Chemie (AU) | |||
| 3 | BA, FA, IA, LA, O... (D, F, G, H, A...) | 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate | non-polymer | 317.4 | 12 | Chemie (E84) | |||
| 4 | CA, P, SA (D, A, J) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 3 | Chemie (BOG) | |||
| 5 | ZA (G) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A, C, E, B, D, F, G, H, I, J, K, L: 1 - 221 (UniProt: Q6DCU6)
| PDB | External Database | Details |
|---|---|---|
| Ser -3 | - | expression tag |
| Val -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 301460.2 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 9413.4 | |
| All* | Total formula weight | 310873.6 |
