7VZB
Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
Summary for 7VZB
Entry DOI | 10.2210/pdb7vzb/pdb |
EMDB information | 32224 |
Descriptor | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, CHOLESTEROL HEMISUCCINATE, S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate (3 entities in total) |
Functional Keywords | very long-chain fatty, peroxisome, abc transporter, transport protein |
Biological source | Caenorhabditis elegans More |
Total number of polymer chains | 2 |
Total formula weight | 179015.66 |
Authors | Chen, Z.P.,Xu, D.,Wang, L.,Mao, Y.X.,Yang, L.,Cheng, M.T.,Hou, W.T.,Chen, Y.X.,Zhou, C.Z. (deposition date: 2021-11-15, release date: 2022-05-18, Last modification date: 2024-06-26) |
Primary citation | Chen, Z.P.,Xu, D.,Wang, L.,Mao, Y.X.,Li, Y.,Cheng, M.T.,Zhou, C.Z.,Hou, W.T.,Chen, Y. Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13:3299-3299, 2022 Cited by PubMed: 35676282DOI: 10.1038/s41467-022-30974-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.59 Å) |
Structure validation
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