7VZB
Cryo-EM structure of C22:0-CoA bound human very long-chain fatty acid ABC transporter ABCD1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 | polymer | 789 | 87931.0 | 2 | UniProt (O45730) UniProt (P33897) Pfam (PF06472) Pfam (PF00005) In PDB | Caenorhabditis elegans | Adrenoleukodystrophy protein,ALDP |
| 2 | A, B | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 3 | A, B | S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethyl] docosanethioate | non-polymer | 1090.1 | 2 | Chemie (FFI) |
Sequence modifications
A, B: 0 - 63 (UniProt: O45730)
A, B: 64 - 745 (UniProt: P33897)
| PDB | External Database | Details |
|---|---|---|
| Met -43 | - | initiating methionine |
| Ala -42 | - | expression tag |
| Ser -41 | - | expression tag |
| Trp -40 | - | expression tag |
| Ser -39 | - | expression tag |
| His -38 | - | expression tag |
| Pro -37 | - | expression tag |
| Gln -36 | - | expression tag |
| Phe -35 | - | expression tag |
| Glu -34 | - | expression tag |
| Lys -33 | - | expression tag |
| Gly -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Ala -29 | - | expression tag |
| Arg -28 | - | expression tag |
| Gly -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Trp -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Gln -16 | - | expression tag |
| Phe -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Lys -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Tyr -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Asp -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Thr -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 175862.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3153.7 | |
| All* | Total formula weight | 179015.7 |
