7UZC

Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34

Summary for 7UZC

Entry DOI	10.2210/pdb7uzc/pdb
Descriptor	Spike protein S1, M8a-34 Fab heavy chain, M8a-34 Fab light chain, ... (6 entities in total)
Functional Keywords	immune system, neutralizing antibody, immune system-viral protein complex, immune system/viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	6
Total formula weight	152574.29
Authors	Fan, C.,Bjorkman, P.J. (deposition date: 2022-05-08, release date: 2023-01-11, Last modification date: 2023-10-25)
Primary citation	Fan, C.,Cohen, A.A.,Park, M.,Hung, A.F.,Keeffe, J.R.,Gnanapragasam, P.N.P.,Lee, Y.E.,Gao, H.,Kakutani, L.M.,Wu, Z.,Kleanthous, H.,Malecek, K.E.,Williams, J.C.,Bjorkman, P.J. Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes. Immunity, 55:2419-2435.e10, 2022 Cited by PubMed: 36370711 DOI: 10.1016/j.immuni.2022.10.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation