7UZC

Structure of the SARS-CoV-2 RBD in complex with the mouse antibody Fab fragment, M8a-34

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Spike protein S1	polymer	231	25994.3	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
2	C, E (E, H)	M8a-34 Fab heavy chain	polymer	235	25507.5	2		Mus musculus
3	D, F (F, L)	M8a-34 Fab light chain	polymer	218	23955.6	2		Mus musculus (house mouse)
4	G (C)	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G10756ZZ)
5	H (D)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
6	I, J, K, L, M... (A, B, E, F, H...)	water	water		18.0	487	Chemie (HOH)

Sequence modifications

A, B: 328 - 533 (UniProt: P0DTC2)

PDB	External Database	Details
Met 309	-	initiating methionine
Gly 310	-	expression tag
Trp 311	-	expression tag
Ser 312	-	expression tag
Cys 313	-	expression tag
Ile 314	-	expression tag
Ile 315	-	expression tag
Leu 316	-	expression tag
Phe 317	-	expression tag
Leu 318	-	expression tag
Val 319	-	expression tag
Ala 320	-	expression tag
Thr 321	-	expression tag
Ala 322	-	expression tag
Thr 323	-	expression tag
Gly 324	-	expression tag
Val 325	-	expression tag
His 326	-	expression tag
Ser 327	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
His 539	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	150914.8
Branched	Number of molecules	2
	Total formula weight	1659.5
All*	Total formula weight	152574.3

*Water molecules are not included.