7U2K

C6-guano bound Mu Opioid Receptor-Gi Protein Complex

Summary for 7U2K

Entry DOI	10.2210/pdb7u2k/pdb
EMDB information	26313
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Mu-type opioid receptor, ... (5 entities in total)
Functional Keywords	gpcr, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	126343.97
Authors	Wang, H.,Kobilka, B. (deposition date: 2022-02-24, release date: 2022-12-07, Last modification date: 2023-02-08)
Primary citation	Faouzi, A.,Wang, H.,Zaidi, S.A.,DiBerto, J.F.,Che, T.,Qu, Q.,Robertson, M.J.,Madasu, M.K.,El Daibani, A.,Varga, B.R.,Zhang, T.,Ruiz, C.,Liu, S.,Xu, J.,Appourchaux, K.,Slocum, S.T.,Eans, S.O.,Cameron, M.D.,Al-Hasani, R.,Pan, Y.X.,Roth, B.L.,McLaughlin, J.P.,Skiniotis, G.,Katritch, V.,Kobilka, B.K.,Majumdar, S. Structure-based design of bitopic ligands for the μ-opioid receptor. Nature, 613:767-774, 2023 Cited by PubMed: 36450356 DOI: 10.1038/s41586-022-05588-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation