7TD8
Integrin alaphIIBbeta3 complex with Tirofiban
Summary for 7TD8
Entry DOI | 10.2210/pdb7td8/pdb |
Related | 7TCT |
Descriptor | Integrin alpha-IIb, SULFATE ION, MAGNESIUM ION, ... (13 entities in total) |
Functional Keywords | complex, inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 300871.24 |
Authors | Zhu, J.,Lin, F.-Y.,Zhu, J.,Springer, T.A. (deposition date: 2021-12-30, release date: 2022-08-17, Last modification date: 2023-10-25) |
Primary citation | Lin, F.Y.,Li, J.,Xie, Y.,Zhu, J.,Huong Nguyen, T.T.,Zhang, Y.,Zhu, J.,Springer, T.A. A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185:3533-3550.e27, 2022 Cited by PubMed: 36113427DOI: 10.1016/j.cell.2022.08.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
Download full validation report