7TD8

Integrin alaphIIBbeta3 complex with Tirofiban

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Integrin alpha-IIb	polymer	453	49129.5	2	UniProt (P08514) Pfam (PF01839) In PDB	Homo sapiens (human)
2	B, D	Integrin beta-3	polymer	471	51958.8	2	UniProt (P05106) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIIa,GPIIIa
3	E, H	Fab heavy chain	polymer	216	23339.1	2		Mus musculus (mouse)
4	F, L	Fab light chain	polymer	214	23332.7	2		Mus musculus (mouse)
5	G	beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G89225LT)
6	I, K	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
7	J	beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G31886NL)
8	C, D, A, B	CALCIUM ION	non-polymer		40.1	12	Chemie (CA)
9	D, A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
10	C, A	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
11	D, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
12	B, D	TIROFIBAN	non-polymer		440.6	2	Chemie (AGG)
13		water	water		18.0	781	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	295520.1
Branched	Number of molecules	4
	Total formula weight	2508.3
Non-Polymers*	Number of molecules	27
	Total formula weight	2842.9
All*	Total formula weight	300871.2

*Water molecules are not included.