7TAZ
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor
Summary for 7TAZ
Entry DOI | 10.2210/pdb7taz/pdb |
Descriptor | Reverse transcriptase/ribonuclease H, Reverse transcriptase p51, 2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]-N-(2-chloro-4-sulfamoylphenyl)acetamide, ... (4 entities in total) |
Functional Keywords | reverse transcriptase, hiv-1, polymerase, nnrti, vm-1500, elsulfavirine, viral protein, transferase-inhibitor complex, transferase/inhibitor |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 2 |
Total formula weight | 114659.00 |
Authors | Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Sarafianos, S.G. (deposition date: 2021-12-21, release date: 2023-04-12, Last modification date: 2023-10-25) |
Primary citation | Snyder, A.A.,Risener, C.J.,Kirby, K.A.,Stefan, S.G. Crystal structure of HIV-1 reverse transcriptase (RT) in complex with VM-1500A, a non-nucleoside RT inhibitor To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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