7T66
Co-crystal structure of Chaetomium glucosidase with compound UV-4
This is a non-PDB format compatible entry.
Summary for 7T66
Entry DOI | 10.2210/pdb7t66/pdb |
Descriptor | Chaetomium alpha glucosidase, GLYCEROL, N-9'-methoxynonyl-1-deoxynojirimycin, ... (7 entities in total) |
Functional Keywords | alpha glucosidase i, hydrolase, inhibitor complex, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Chaetomium thermophilum var. thermophilum DSM 1495 |
Total number of polymer chains | 2 |
Total formula weight | 188853.76 |
Authors | Karade, S.S.,Mariuzza, R.A. (deposition date: 2021-12-13, release date: 2022-05-04, Last modification date: 2023-10-18) |
Primary citation | Karade, S.S.,Kolesnikov, A.,Treston, A.M.,Mariuzza, R.A. Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design. Biochemistry, 61:822-832, 2022 Cited by PubMed: 35476408DOI: 10.1021/acs.biochem.2c00092 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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