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8F7V

Macrocyclic plasmin inhibitor

Replaces:  7T52
Summary for 8F7V
Entry DOI10.2210/pdb8f7v/pdb
DescriptorPlasminogen, (6S,9R,19S,22R)-N-{[4-(aminomethyl)phenyl]methyl}-22-[(benzenesulfonyl)amino]-3,12,21-trioxo-2,6,9,13,20-pentaazatetracyclo[22.2.2.2~6,9~.2~14,17~]dotriaconta-1(26),14,16,24,27,29-hexaene-19-carboxamide, SULFATE ION, ... (5 entities in total)
Functional Keywordsprotease, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total formula weight57185.39
Authors
Guojie, W. (deposition date: 2022-11-20, release date: 2023-02-08, Last modification date: 2024-11-06)
Primary citationGuojie, W.
Synthesis and structural characterization of new macrocyclicplasmin inhibitors
Chemmedchem, 2023
Experimental method
X-RAY DIFFRACTION (1.65 Å)
Structure validation

227344

PDB entries from 2024-11-13

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