7T4G
The Envelope Glycoprotein SIVmac239.K180S SOSIP trimer in complex with 3 copies of the neutralizing antibody K11
Summary for 7T4G
Entry DOI | 10.2210/pdb7t4g/pdb |
EMDB information | 25676 |
Descriptor | Envelope glycoprotein gp120, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total) |
Functional Keywords | siv, env, vaccine, neutralizing antibody, glycoprotein, viral protein-immune system complex, viral protein/immune system |
Biological source | Simian immunodeficiency virus More |
Total number of polymer chains | 12 |
Total formula weight | 505372.60 |
Authors | Berndsen, Z.T.,Ward, A.B. (deposition date: 2021-12-09, release date: 2022-10-19, Last modification date: 2023-07-05) |
Primary citation | Zhao, F.,Berndsen, Z.T.,Pedreno-Lopez, N.,Burns, A.,Allen, J.D.,Barman, S.,Lee, W.H.,Chakraborty, S.,Gnanakaran, S.,Sewall, L.M.,Ozorowski, G.,Limbo, O.,Song, G.,Yong, P.,Callaghan, S.,Coppola, J.,Weisgrau, K.L.,Lifson, J.D.,Nedellec, R.,Voigt, T.B.,Laurino, F.,Louw, J.,Rosen, B.C.,Ricciardi, M.,Crispin, M.,Desrosiers, R.C.,Rakasz, E.G.,Watkins, D.I.,Andrabi, R.,Ward, A.B.,Burton, D.R.,Sok, D. Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus. Nat Commun, 13:5236-5236, 2022 Cited by PubMed: 36068229DOI: 10.1038/s41467-022-32783-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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