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7T3N

R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2)

Summary for 7T3N
Entry DOI10.2210/pdb7t3n/pdb
Related6V4D
EMDB information25665 25666
DescriptorVesicular glutamate transporter 2, (1S,3R)-1-AMINOCYCLOPENTANE-1,3-DICARBOXYLIC ACID, (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside (3 entities in total)
Functional Keywordssynaptic vesicle, neurotransmitter, glutamate transport, transport protein
Biological sourceRattus norvegicus (Norway rat)
Total number of polymer chains1
Total formula weight65873.86
Authors
Li, F.,Stroud, R.M.,Edwards, R.H. (deposition date: 2021-12-08, release date: 2022-12-14)
Primary citationLi, F.,Stroud, R.M.
Substrate Recognition, Directional Flux, and Allostery in a Synaptic Vesicle Glutamate Transporter
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3 Å)
Structure validation

227344

PDB entries from 2024-11-13

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