7SWD
Structure of EBOV GP lacking the mucin-like domain with 1C11 scFv and 1C3 Fab bound
Summary for 7SWD
Entry DOI | 10.2210/pdb7swd/pdb |
EMDB information | 25471 |
Descriptor | Virion spike glycoprotein GP1, Virion spike glycoprotein GP2, 1C11 scFv, ... (6 entities in total) |
Functional Keywords | viral protein, glycoprotein, immune system, antibody, ebola virus, viral protein-immune system complex, viral protein/immune system |
Biological source | Ebola virus - Gabon (1994-1997) More |
Total number of polymer chains | 11 |
Total formula weight | 234204.04 |
Authors | Milligan, J.C.,Yu, X.,Saphire, E.O. (deposition date: 2021-11-19, release date: 2022-04-06, Last modification date: 2022-08-10) |
Primary citation | Milligan, J.C.,Davis, C.W.,Yu, X.,Ilinykh, P.A.,Huang, K.,Halfmann, P.J.,Cross, R.W.,Borisevich, V.,Agans, K.N.,Geisbert, J.B.,Chennareddy, C.,Goff, A.J.,Piper, A.E.,Hui, S.,Shaffer, K.C.L.,Buck, T.,Heinrich, M.L.,Branco, L.M.,Crozier, I.,Holbrook, M.R.,Kuhn, J.H.,Kawaoka, Y.,Glass, P.J.,Bukreyev, A.,Geisbert, T.W.,Worwa, G.,Ahmed, R.,Saphire, E.O. Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses. Cell, 185:995-1007.e18, 2022 Cited by PubMed: 35303429DOI: 10.1016/j.cell.2022.02.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.59 Å) |
Structure validation
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