7SBF
PZM21 bound Mu Opioid Receptor-Gi Protein Complex
Summary for 7SBF
Entry DOI | 10.2210/pdb7sbf/pdb |
EMDB information | 24978 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 169217.50 |
Authors | Huang, W.,Qu, Q.,Wang, H.,Skiniotis, G.,Kobilka, B. (deposition date: 2021-09-24, release date: 2022-04-20, Last modification date: 2022-07-06) |
Primary citation | Wang, H.,Hetzer, F.,Huang, W.,Qu, Q.,Meyerowitz, J.,Kaindl, J.,Hubner, H.,Skiniotis, G.,Kobilka, B.K.,Gmeiner, P. Structure-Based Evolution of G Protein-Biased mu-Opioid Receptor Agonists. Angew.Chem.Int.Ed.Engl., 61:e202200269-e202200269, 2022 Cited by PubMed: 35385593DOI: 10.1002/anie.202200269 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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