7RPJ
Cryo-EM structure of murine Dispatched NNN mutant
Summary for 7RPJ
Entry DOI | 10.2210/pdb7rpj/pdb |
EMDB information | 24614 24615 24616 24617 |
Descriptor | Protein dispatched homolog 1, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE (3 entities in total) |
Functional Keywords | rnd transporter, hedgehog binding, sterol sensing domain, sodium binding, membrane protein |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 159988.39 |
Authors | Asarnow, D.,Wang, Q.,Ding, K.,Cheng, Y.,Beachy, P.A. (deposition date: 2021-08-03, release date: 2021-10-27, Last modification date: 2021-11-24) |
Primary citation | Wang, Q.,Asarnow, D.E.,Ding, K.,Mann, R.K.,Hatakeyama, J.,Zhang, Y.,Ma, Y.,Cheng, Y.,Beachy, P.A. Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599:320-324, 2021 Cited by PubMed: 34707294DOI: 10.1038/s41586-021-03996-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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