7RKS
Structure of the SARS-CoV receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118
Summary for 7RKS
Entry DOI | 10.2210/pdb7rks/pdb |
Descriptor | C118 Antibody Fab Heavy Chain, C118 Antibody Fab Light Chain, Spike protein S1, ... (5 entities in total) |
Functional Keywords | antibody, surface protein, fab, coronavirus, fusion protein, binding domain, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 142586.78 |
Authors | Jette, C.A.,Bjorkman, P.J.,Barnes, C.O. (deposition date: 2021-07-22, release date: 2021-09-22, Last modification date: 2023-10-18) |
Primary citation | Jette, C.A.,Cohen, A.A.,Gnanapragasam, P.N.P.,Muecksch, F.,Lee, Y.E.,Huey-Tubman, K.E.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Nussenzweig, M.C.,West Jr., A.P.,Keeffe, J.R.,Bjorkman, P.J.,Barnes, C.O. Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. Cell Rep, 36:109760-109760, 2021 Cited by PubMed: 34534459DOI: 10.1016/j.celrep.2021.109760 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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