7R7P
Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6)
Summary for 7R7P
Entry DOI | 10.2210/pdb7r7p/pdb |
NMR Information | BMRB: 30929 |
Descriptor | Gag polyprotein, INOSITOL HEXAKISPHOSPHATE, 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid (3 entities in total) |
Functional Keywords | hiv-1 capsid, maturation inhibitors, hiv-aids, protein binding |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 6 |
Total formula weight | 67812.89 |
Authors | Sarkar, S.,Zadrozny, K.K.,Zadorozhnyi, R.,Russell, R.W.,Quinn, C.M.,Kleinpeter, A.,Ablan, S.,Meshkin, H.,Perilla, J.R.,Ganser-Pornillos, B.K.,Pornillos, O.,Freed, E.O.,Gronenborn, A.M.,Polenova, T. (deposition date: 2021-06-25, release date: 2023-02-15, Last modification date: 2024-05-15) |
Primary citation | Sarkar, S.,Zadrozny, K.K.,Zadorozhnyi, R.,Russell, R.W.,Quinn, C.M.,Kleinpeter, A.,Ablan, S.,Meshkin, H.,Perilla, J.R.,Freed, E.O.,Ganser-Pornillos, B.K.,Pornillos, O.,Gronenborn, A.M.,Polenova, T. Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun, 14:1237-1237, 2023 Cited by PubMed: 36871077DOI: 10.1038/s41467-023-36569-y PDB entries with the same primary citation |
Experimental method | SOLID-STATE NMR |
Structure validation
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