7R55
B-trefoil lectin from Salpingoeca rosetta in complex with Gb3
This is a non-PDB format compatible entry.
Summary for 7R55
Entry DOI | 10.2210/pdb7r55/pdb |
Descriptor | Sarol-1, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | lectin, gb3, b-trefoil, pore forming lectin, sugar binding protein |
Biological source | Salpingoeca rosetta |
Total number of polymer chains | 2 |
Total formula weight | 75115.39 |
Authors | Notova, S.,Varrot, A. (deposition date: 2022-02-10, release date: 2022-09-14, Last modification date: 2024-01-31) |
Primary citation | Notova, S.,Bonnardel, F.,Rosato, F.,Siukstaite, L.,Schwaiger, J.,Lim, J.H.,Bovin, N.,Varrot, A.,Ogawa, Y.,Romer, W.,Lisacek, F.,Imberty, A. The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3. Commun Biol, 5:954-954, 2022 Cited by PubMed: 36097056DOI: 10.1038/s42003-022-03869-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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