7QNG
Structure of a MHC I-Tapasin-ERp57 complex
Summary for 7QNG
Entry DOI | 10.2210/pdb7qng/pdb |
Descriptor | Tapasin, Protein disulfide-isomerase A3, H-2 class I histocompatibility antigen, D-B alpha chain, ... (6 entities in total) |
Functional Keywords | mhc i, chaperone complex, endoplasmic reticulum, peptide editing, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 146396.96 |
Authors | Mueller, I.K.,Thomas, C.,Trowitzsch, S.,Tampe, R. (deposition date: 2021-12-20, release date: 2022-09-28, Last modification date: 2024-01-31) |
Primary citation | Muller, I.K.,Winter, C.,Thomas, C.,Spaapen, R.M.,Trowitzsch, S.,Tampe, R. Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity. Nat Commun, 13:5383-5383, 2022 Cited by PubMed: 36104323DOI: 10.1038/s41467-022-32841-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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