7QKR
Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution
Summary for 7QKR
Entry DOI | 10.2210/pdb7qkr/pdb |
EMDB information | 14049 |
Descriptor | Plasma membrane ATP-binding cassette transporter required for the export of a-factor, Dexverapamil, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
Functional Keywords | abc transporter, abcb, mdr, membrane protein, pichia pastoris, transport protein |
Biological source | Komagataella phaffii CBS 7435 |
Total number of polymer chains | 1 |
Total formula weight | 146504.17 |
Authors | Schleker, E.S.M.,Reinhart, C. (deposition date: 2021-12-18, release date: 2022-10-26, Last modification date: 2024-07-17) |
Primary citation | Schleker, E.S.M.,Buschmann, S.,Xie, H.,Welsch, S.,Michel, H.,Reinhart, C. Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proc.Natl.Acad.Sci.USA, 119:e2202822119-e2202822119, 2022 Cited by PubMed: 36256814DOI: 10.1073/pnas.2202822119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report