7QEE
SN243 mutant D415N bound to para-nitrophenyl-Beta-D-glucuronide
Summary for 7QEE
Entry DOI | 10.2210/pdb7qee/pdb |
Descriptor | SN243, ZINC ION, SULFATE ION, ... (6 entities in total) |
Functional Keywords | enzyme discovery, carbohydrate-active enzymes (cazy), protein engineering, functional metagenomics), hydrolase |
Biological source | Synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 166618.12 |
Authors | Neun, S.,Brear, P.,Campbell, E.,Omari, K.,Wagner, O.,Hyvonen, M.,Hollfelder, F. (deposition date: 2021-12-02, release date: 2022-11-16, Last modification date: 2024-01-31) |
Primary citation | Neun, S.,Brear, P.,Campbell, E.,Tryfona, T.,El Omari, K.,Wagner, A.,Dupree, P.,Hyvonen, M.,Hollfelder, F. Functional metagenomic screening identifies an unexpected beta-glucuronidase. Nat.Chem.Biol., 18:1096-1103, 2022 Cited by PubMed: 35799064DOI: 10.1038/s41589-022-01071-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.374 Å) |
Structure validation
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