7ORT

Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ176

Summary for 7ORT

• Entry DOI: 10.2210/pdb7ort/pdb
• Descriptor: 14-3-3 protein sigma, Cyclin-dependent kinase inhibitor 1B, ~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]-2-(1~{H}-indol-6-yl)ethanamide, ... (6 entities in total)
• Functional Keywords: protein-peptide complex small-molecule, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 30221.78

Authors

Centorrino, F.,Wu, Q.,Ottmann, C. (deposition date: 2021-06-06, release date: 2022-06-22, Last modification date: 2024-01-31)

• Primary citation: Centorrino, F.,Wu, Q.,Cossar, P.,Brunsveld, L.,Ottmann, C.; A crystallography-based study of fragment extensions into the 14-3-3 binding groove; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)