7OA1
Crystal structure of alfa carbonic anhydrase from Schistosoma mansoni with 4-(2-(3-(4-iodophenyl)ureido)ethyl)benzenesulfonamide
This is a non-PDB format compatible entry.
Summary for 7OA1
Entry DOI | 10.2210/pdb7oa1/pdb |
Descriptor | Carbonic anhydrase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (7 entities in total) |
Functional Keywords | carbonic anhydrase, inhibitor, schistosoma mansoni, lyase |
Biological source | Schistosoma mansoni (Blood fluke) |
Total number of polymer chains | 2 |
Total formula weight | 74053.71 |
Authors | Angelil, A.,Ferraroni, M. (deposition date: 2021-04-18, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Angeli, A.,Ferraroni, M.,Da'dara, A.A.,Selleri, S.,Pinteala, M.,Carta, F.,Skelly, P.J.,Supuran, C.T. Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides. J.Med.Chem., 64:10418-10428, 2021 Cited by PubMed: 34232641DOI: 10.1021/acs.jmedchem.1c00840 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report