7OA1
Crystal structure of alfa carbonic anhydrase from Schistosoma mansoni with 4-(2-(3-(4-iodophenyl)ureido)ethyl)benzenesulfonamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AAA, BBB) | Carbonic anhydrase | polymer | 312 | 35704.9 | 2 | UniProt (A0A3Q0KSG2) Pfam (PF00194) | Schistosoma mansoni (Blood fluke) | |
| 2 | C (GGG) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, I (AAA, BBB) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F, G, J, K (AAA, BBB) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 5 | H, M (AAA, BBB) | 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]urea | non-polymer | 445.3 | 2 | Chemie (TKQ) | |||
| 6 | L (BBB) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | N, O (AAA, BBB) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
AAA, BBB: 21 - 298 (UniProt: A0A3Q0KSG2)
| PDB | External Database | Details |
|---|---|---|
| Asp 12 | - | expression tag |
| Ala 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Gln 15 | - | expression tag |
| Pro 16 | - | expression tag |
| Ala 17 | - | expression tag |
| Arg 18 | - | expression tag |
| Arg 19 | - | expression tag |
| Ala 20 | - | expression tag |
| Arg 299 | - | expression tag |
| Gly 300 | - | expression tag |
| Gly 301 | - | expression tag |
| Pro 302 | - | expression tag |
| Glu 303 | - | expression tag |
| Gln 304 | - | expression tag |
| Lys 305 | - | expression tag |
| Leu 306 | - | expression tag |
| Ile 307 | - | expression tag |
| Ser 308 | - | expression tag |
| Glu 309 | - | expression tag |
| Glu 310 | - | expression tag |
| Asp 311 | - | expression tag |
| Leu 312 | - | expression tag |
| Asn 313 | - | expression tag |
| Ser 314 | - | expression tag |
| Ala 315 | - | expression tag |
| Val 316 | - | expression tag |
| Asp 317 | - | expression tag |
| His 318 | - | expression tag |
| His 319 | - | expression tag |
| His 320 | - | expression tag |
| His 321 | - | expression tag |
| His 322 | - | expression tag |
| His 323 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71409.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2219.5 | |
| All* | Total formula weight | 74053.7 |
