7O9Y
Crystal structure of di-phosphorylated human CLK1 in complex with 4-(1H-indol-3-yl)pyrimidin-2-amine
Summary for 7O9Y
Entry DOI | 10.2210/pdb7o9y/pdb |
Related | 6QTY 6R3D 6R6E 6R6X 6R8J |
Descriptor | Dual specificity protein kinase CLK1, 4-(1~{H}-indol-3-yl)pyrimidin-2-amine (3 entities in total) |
Functional Keywords | clk1, splicing, kinase, viral infection, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 39659.59 |
Authors | Livnah, O.,Domovich, Y.,Bracher, F.,Aiger, C. (deposition date: 2021-04-18, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Livnah, O.,Domovich, Y.,Bracher, F.,Aiger, C. Development of novel CLK1 inhibitors as potential drugs for treatment of Chikungunya virus infections To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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