7O4G
Human phosphomannomutase 2 (PMM2) wild-type soaked with the activator glucose 1,6-bisphosphate
Summary for 7O4G
Entry DOI | 10.2210/pdb7o4g/pdb |
Descriptor | Phosphomannomutase 2, GLYCEROL, MAGNESIUM ION, ... (7 entities in total) |
Functional Keywords | glycobiology, congenital disorders of glycosylation, phosphotransferase, phosphomutase, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 57135.54 |
Authors | Ramon-Maiques, S.,Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Perez, B.,Rubio, V. (deposition date: 2021-04-06, release date: 2022-02-02, Last modification date: 2024-01-31) |
Primary citation | Briso-Montiano, A.,Del Cano-Ochoa, F.,Vilas, A.,Velazquez-Campoy, A.,Rubio, V.,Perez, B.,Ramon-Maiques, S. Insight on molecular pathogenesis and pharmacochaperoning potential in phosphomannomutase 2 deficiency, provided by novel human phosphomannomutase 2 structures. J Inherit Metab Dis, 45:318-333, 2022 Cited by PubMed: 34859900DOI: 10.1002/jimd.12461 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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