7O2X
Crystal structure of the human METTL3-METTL14 complex with compound T180
Summary for 7O2X
Entry DOI | 10.2210/pdb7o2x/pdb |
Descriptor | N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, N-[(6-methylimidazo[1,2-a]pyridin-2-yl)methyl]-4-oxidanylidene-pyrido[1,2-a]pyrimidine-2-carboxamide, ... (5 entities in total) |
Functional Keywords | mettl3, inhibitor, complex, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 62157.71 |
Authors | Bedi, R.K.,Huang, D.,Caflisch, A. (deposition date: 2021-03-31, release date: 2021-04-07, Last modification date: 2024-01-31) |
Primary citation | Bedi, R.K.,Huang, D.,Caflisch, A. Crystal structure of the human METTL3-METTL14 complex with compound T180 To Be Published, |
Experimental method |
Structure validation
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