7NTB
Crystal structure of human carbonic anhydrase with a benzophenone-derivative
Summary for 7NTB
Entry DOI | 10.2210/pdb7ntb/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, ~{N}-[[4-(phenylcarbonyl)phenyl]methyl]-4-sulfamoyl-benzamide, ... (5 entities in total) |
Functional Keywords | protein-inhibitor adduct, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29939.42 |
Authors | Di Fiore, A.,De Simone, G. (deposition date: 2021-03-09, release date: 2022-03-16, Last modification date: 2024-01-31) |
Primary citation | Pagnozzi, D.,Pala, N.,Biosa, G.,Dallocchio, R.,Dessi, A.,Singh, P.K.,Rogolino, D.,Di Fiore, A.,De Simone, G.,Supuran, C.T.,Sechi, M. Interaction Studies between Carbonic Anhydrase and a Sulfonamide Inhibitor by Experimental and Theoretical Approaches Acs Med.Chem.Lett., 13:271-277, 2022 Cited by DOI: 10.1021/acsmedchemlett.1c00644PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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