7NNR
Crystal structure of Mycobacterium tuberculosis ArgC in complex with xanthene-9-carboxylic acid
Summary for 7NNR
Entry DOI | 10.2210/pdb7nnr/pdb |
Descriptor | N-acetyl-gamma-glutamyl-phosphate reductase, 9~{H}-xanthene-9-carboxylic acid, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total) |
Functional Keywords | argc, n-acetyl-gamma-glutamyl-phosphate reductase, nagpr, arginine biosynthesis, oxidoreductase |
Biological source | Mycobacterium tuberculosis H37Rv |
Total number of polymer chains | 2 |
Total formula weight | 73841.54 |
Authors | Gupta, P.,Mendes, V.,Blundell, T.L. (deposition date: 2021-02-25, release date: 2021-06-30, Last modification date: 2024-01-31) |
Primary citation | Gupta, P.,Thomas, S.E.,Zaidan, S.A.,Pasillas, M.A.,Cory-Wright, J.,Sebastian-Perez, V.,Burgess, A.,Cattermole, E.,Meghir, C.,Abell, C.,Coyne, A.G.,Jacobs, W.R.,Blundell, T.L.,Tiwari, S.,Mendes, V. A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19:3491-3506, 2021 Cited by DOI: 10.1016/j.csbj.2021.06.006PDB entries with the same primary citation |
Experimental method |
Structure validation
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