7NDW
ThyX-FADH2 soaked with 20 mM Formaldehyde
Summary for 7NDW
Entry DOI | 10.2210/pdb7ndw/pdb |
Descriptor | Flavin-dependent thymidylate synthase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-[5-methanoyl-7,8-dimethyl-2,4-bis(oxidanylidene)-1H-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate, DI(HYDROXYETHYL)ETHER, ... (7 entities in total) |
Functional Keywords | flavin-dependent thymidylate synthase, methylenetetrahydrofolate, transferase |
Biological source | Thermotoga maritima |
Total number of polymer chains | 4 |
Total formula weight | 114442.98 |
Authors | Bou-Nader, C.,Pecqueur, L.,Hamdane, D. (deposition date: 2021-02-02, release date: 2021-07-21, Last modification date: 2024-01-31) |
Primary citation | Bou-Nader, C.,Stull, F.W.,Pecqueur, L.,Simon, P.,Guerineau, V.,Royant, A.,Fontecave, M.,Lombard, M.,Palfey, B.A.,Hamdane, D. An enzymatic activation of formaldehyde for nucleotide methylation. Nat Commun, 12:4542-4542, 2021 Cited by PubMed: 34315871DOI: 10.1038/s41467-021-24756-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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