7NDW
ThyX-FADH2 soaked with 20 mM Formaldehyde
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Flavin-dependent thymidylate synthase | polymer | 232 | 27503.7 | 4 | UniProt (Q9WYT0) Pfam (PF02511) In PDB | Thermotoga maritima | FDTS,FAD-dependent thymidylate synthase,Thymidylate synthase ThyX,TSase |
2 | A, B | [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4S)-5-[5-methanoyl-7,8-dimethyl-2,4-bis(oxidanylidene)-1H-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | non-polymer | 815.6 | 2 | Chemie (HUF) | |||
3 | A, B, D | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 7 | Chemie (PEG) | |||
4 | B, C, D | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
5 | C, D | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | non-polymer | 787.6 | 2 | Chemie (FDA) | |||
6 | C | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
7 | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 220 (UniProt: Q9WYT0)
PDB | External Database | Details |
---|---|---|
Met -11 | - | initiating methionine |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
Asp -8 | - | expression tag |
Lys -7 | - | expression tag |
Ile -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 110014.7 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 4428.3 | |
All* | Total formula weight | 114443.0 |