7NBP
Solution structure of DNA duplex containing a 7,8-dihydro-8-oxo-1,N6-ethenoadenine base modification that induces exclusively A->T transversions in Escherichia coli
Summary for 7NBP
Entry DOI | 10.2210/pdb7nbp/pdb |
NMR Information | BMRB: 34596 |
Descriptor | DNA (5'-D(*GP*TP*AP*CP*(EDA)P*CP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*GP*AP*GP*TP*AP*C)-3') (2 entities in total) |
Functional Keywords | modified dna, dna |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 5503.67 |
Authors | Aralov, A.V.,Gubina, N.,Cabrero, C.,Tsvetkov, V.B.,Turaev, A.V.,Fedeles, B.I.,Croy, R.G.,Isaakova, E.A.,Melnik, D.,Dukova, S.,Khrulev, A.A.,Varizhuk, A.M.,Gonzalez, C.,Zatsepin, T.S.,Essigmann, J.M. (deposition date: 2021-01-27, release date: 2022-03-02, Last modification date: 2024-06-19) |
Primary citation | Aralov, A.V.,Gubina, N.,Cabrero, C.,Tsvetkov, V.B.,Turaev, A.V.,Fedeles, B.I.,Croy, R.G.,Isaakova, E.A.,Melnik, D.,Dukova, S.,Ryazantsev, D.Y.,Khrulev, A.A.,Varizhuk, A.M.,Gonzalez, C.,Zatsepin, T.S.,Essigmann, J.M. 7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli. Nucleic Acids Res., 50:3056-3069, 2022 Cited by PubMed: 35234900DOI: 10.1093/nar/gkac148 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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