7MDC
Full-length wildtype ClbP inhibited by hexanoyl-D-asparagine boronic acid
Summary for 7MDC
Entry DOI | 10.2210/pdb7mdc/pdb |
Related | 7MDE 7MDF 7UL6 |
Descriptor | Beta-lactamase, NONAETHYLENE GLYCOL, DIMETHYL SULFOXIDE, ... (8 entities in total) |
Functional Keywords | colibactin peptidase, s12 peptidase, boronic acid inhibitor, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 56711.25 |
Authors | Velilla, J.A.,Volpe, M.R.,Gaudet, R. (deposition date: 2021-04-03, release date: 2022-09-28, Last modification date: 2023-10-25) |
Primary citation | Volpe, M.R.,Velilla, J.A.,Daniel-Ivad, M.,Yao, J.J.,Stornetta, A.,Villalta, P.W.,Huang, H.C.,Bachovchin, D.A.,Balbo, S.,Gaudet, R.,Balskus, E.P. A small molecule inhibitor prevents gut bacterial genotoxin production. Nat.Chem.Biol., 19:159-167, 2023 Cited by PubMed: 36253549DOI: 10.1038/s41589-022-01147-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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