7LB0
Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295
Summary for 7LB0
Entry DOI | 10.2210/pdb7lb0/pdb |
Descriptor | Transcription initiation factor TFIID subunit 1, 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | bromodomain, taf1, tbp, transcription, general transcription factor iid, tfiid, tf250, non-bet, atr, kinase, gene regulation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31444.81 |
Authors | Karim, M.R.,Schonbrunn, E. (deposition date: 2021-01-07, release date: 2021-07-14, Last modification date: 2023-10-18) |
Primary citation | Karim, M.R.,Schonbrunn, E. Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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