7L2E
Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
Summary for 7L2E
Entry DOI | 10.2210/pdb7l2e/pdb |
EMDB information | 23126 |
Descriptor | Spike glycoprotein, 4-18 heavy chain, 4-18 light chain, ... (5 entities in total) |
Functional Keywords | neutralizing antibody, fusion protein, spike glycoprotein, covid-19, ntd, ntd-directed antibody, 4-18, viral protein, immune system, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 9 |
Total formula weight | 586621.15 |
Authors | Cerutti, G.,Shapiro, L. (deposition date: 2020-12-16, release date: 2021-03-24, Last modification date: 2021-05-26) |
Primary citation | Cerutti, G.,Guo, Y.,Zhou, T.,Gorman, J.,Lee, M.,Rapp, M.,Reddem, E.R.,Yu, J.,Bahna, F.,Bimela, J.,Huang, Y.,Katsamba, P.S.,Liu, L.,Nair, M.S.,Rawi, R.,Olia, A.S.,Wang, P.,Zhang, B.,Chuang, G.Y.,Ho, D.D.,Sheng, Z.,Kwong, P.D.,Shapiro, L. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29:819-, 2021 Cited by PubMed: 33789084DOI: 10.1016/j.chom.2021.03.005 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.97 Å) |
Structure validation
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