7KGB
CryoEM structure of A2296-methylated Mycobacterium tuberculosis ribosome bound with SEQ-9
This is a non-PDB format compatible entry.
Summary for 7KGB
Entry DOI | 10.2210/pdb7kgb/pdb |
EMDB information | 22865 |
Descriptor | 50S ribosomal protein L32, 50S ribosomal protein L3, 50S ribosomal protein L4, ... (55 entities in total) |
Functional Keywords | antibiotic, methylation, pathogen, ribosome, ribosome-antibiotic complex, ribosome/antibiotic |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More |
Total number of polymer chains | 52 |
Total formula weight | 2272100.28 |
Authors | |
Primary citation | Zhang, J.,Lair, C.,Roubert, C.,Amaning, K.,Barrio, M.B.,Benedetti, Y.,Cui, Z.,Xing, Z.,Li, X.,Franzblau, S.G.,Baurin, N.,Bordon-Pallier, F.,Cantalloube, C.,Sans, S.,Silve, S.,Blanc, I.,Fraisse, L.,Rak, A.,Jenner, L.B.,Yusupova, G.,Yusupov, M.,Zhang, J.,Kaneko, T.,Yang, T.J.,Fotouhi, N.,Nuermberger, E.,Tyagi, S.,Betoudji, F.,Upton, A.,Sacchettini, J.C.,Lagrange, S. Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents. Cell, 2023 Cited by PubMed: 36827973DOI: 10.1016/j.cell.2023.01.043 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.7 Å) |
Structure validation
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