7K9J

SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation)

Summary for 7K9J

• Entry DOI: 10.2210/pdb7k9j/pdb
• Related: 7K9H 7K9I 7K9K
• EMDB information: 22748 22749 22750 22751 22752 22753
• Descriptor: Spike glycoprotein, 2H04 heavy chain, 2H04 light chain, ... (9 entities in total)
• Functional Keywords: complex, neutralizing antibody, ace2-non-competitive, receptor-binding domain, viral protein-immune system complex, structural genomics, center for structural genomics of infectious diseases, csgid, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 9
• Total formula weight: 514838.06

Authors

Errico, J.M.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-09-29, release date: 2021-09-29, Last modification date: 2021-11-10)

• Primary citation: Errico, J.M.,Zhao, H.,Chen, R.E.,Liu, Z.,Case, J.B.,Ma, M.,Schmitz, A.J.,Rau, M.J.,Fitzpatrick, J.A.J.,Shi, P.Y.,Diamond, M.S.,Whelan, S.P.J.,Ellebedy, A.H.,Fremont, D.H.; Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD.; Cell Rep, 37:109881-109881, 2021; PubMed: 34655519; DOI: 10.1016/j.celrep.2021.109881

Experimental method

ELECTRON MICROSCOPY (3 Å)