7K5H
1.90 A resolution structure of WT BfrB from Pseudomonas aeruginosa in complex with a protein-protein interaction inhibitor KM-5-66
Summary for 7K5H
Entry DOI | 10.2210/pdb7k5h/pdb |
Descriptor | Ferroxidase, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total) |
Functional Keywords | biofilms, electron transport, iron storage, iron binding, iron mobilization, protein-protein interaction inhibitor, oxidoreductase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 12 |
Total formula weight | 231033.14 |
Authors | Lovell, S.,Battaile, K.P.,Soldano, A.,Punchi-Hewage, A.,Meraz, K.,Annor-Gyamfi, J.K.,Yao, H.,Bunce, R.A.,Rivera, M. (deposition date: 2020-09-16, release date: 2020-12-16, Last modification date: 2023-10-18) |
Primary citation | Soldano, A.,Yao, H.,Punchi Hewage, A.N.D.,Meraz, K.,Annor-Gyamfi, J.K.,Bunce, R.A.,Battaile, K.P.,Lovell, S.,Rivera, M. Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells. Acs Infect Dis., 7:123-140, 2021 Cited by PubMed: 33269912DOI: 10.1021/acsinfecdis.0c00669 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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