7K1D
Crystal structure of human insulin degrading enzyme (IDE) in complex with compound BDM_77291
Summary for 7K1D
Entry DOI | 10.2210/pdb7k1d/pdb |
Descriptor | Insulin-degrading enzyme, ZINC ION, (3R)-3-{4-[(3R)-4-(3,4-difluorobenzene-1-carbonyl)morpholin-3-yl]-1H-1,2,3-triazol-1-yl}-N-hydroxy-4-(naphthalen-2-yl)butanamide, ... (5 entities in total) |
Functional Keywords | hydrolase, inhibitor, hydrolase-hydrolase inhbitor complex, hydrolase/hydrolase inhbitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 231302.21 |
Authors | Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. (deposition date: 2020-09-07, release date: 2021-09-22, Last modification date: 2023-10-18) |
Primary citation | Liang, W.G.,Deprez, R.,Bosc, D.,Tang, W. Crystal structure of human insulin degrading enzyme (IDE) in complex with compound 2 To Be Published, |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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