7JX3
Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology
Summary for 7JX3
Entry DOI | 10.2210/pdb7jx3/pdb |
Descriptor | Light chain of Fab domain of monoclonal antibody S309, Heavy chain of Fab domain of monoclonal antibody S309, Light chain of Fab domain of monoclonal antibody S2H14, ... (9 entities in total) |
Functional Keywords | covid-19, sars-cov-2, neutralizing monoclonal antibody, viral protein-immune system complex, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 7 |
Total formula weight | 165433.84 |
Authors | Snell, G.,Czudnochowski, N.,Rosen, L.E.,Nix, J.C.,Corti, D.,Veesler, D.,Park, Y.J.,Walls, A.C.,Tortorici, M.A.,Cameroni, E.,Pinto, D.,Beltramello, M.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2020-08-26, release date: 2020-10-14, Last modification date: 2024-08-07) |
Primary citation | Piccoli, L.,Park, Y.J.,Tortorici, M.A.,Czudnochowski, N.,Walls, A.C.,Beltramello, M.,Silacci-Fregni, C.,Pinto, D.,Rosen, L.E.,Bowen, J.E.,Acton, O.J.,Jaconi, S.,Guarino, B.,Minola, A.,Zatta, F.,Sprugasci, N.,Bassi, J.,Peter, A.,De Marco, A.,Nix, J.C.,Mele, F.,Jovic, S.,Rodriguez, B.F.,Gupta, S.V.,Jin, F.,Piumatti, G.,Lo Presti, G.,Pellanda, A.F.,Biggiogero, M.,Tarkowski, M.,Pizzuto, M.S.,Cameroni, E.,Havenar-Daughton, C.,Smithey, M.,Hong, D.,Lepori, V.,Albanese, E.,Ceschi, A.,Bernasconi, E.,Elzi, L.,Ferrari, P.,Garzoni, C.,Riva, A.,Snell, G.,Sallusto, F.,Fink, K.,Virgin, H.W.,Lanzavecchia, A.,Corti, D.,Veesler, D. Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. Cell, 183:1024-1042.e21, 2020 Cited by PubMed: 32991844DOI: 10.1016/j.cell.2020.09.037 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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