7F58
Cryo-EM structure of THIQ-MC4R-Gs_Nb35 complex
Summary for 7F58
Entry DOI | 10.2210/pdb7f58/pdb |
EMDB information | 31456 31457 31458 31461 |
Descriptor | Melanocortin receptor 4, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (8 entities in total) |
Functional Keywords | single particle, membrane protein, class a g-protein-coupled receptors |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 164268.49 |
Authors | |
Primary citation | Zhang, H.,Chen, L.N.,Yang, D.,Mao, C.,Shen, Q.,Feng, W.,Shen, D.D.,Dai, A.,Xie, S.,Zhou, Y.,Qin, J.,Sun, J.P.,Scharf, D.H.,Hou, T.,Zhou, T.,Wang, M.W.,Zhang, Y. Structural insights into ligand recognition and activation of the melanocortin-4 receptor. Cell Res., 31:1163-1175, 2021 Cited by PubMed: 34433901DOI: 10.1038/s41422-021-00552-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
Download full validation report