7EXD
Lasmiditan-bound serotonin 1F (5-HT1F) receptor-Gi protein complex
Summary for 7EXD
Entry DOI | 10.2210/pdb7exd/pdb |
EMDB information | 31371 |
Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total) |
Functional Keywords | gpcr, serotonin, gi, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 170654.99 |
Authors | |
Primary citation | Huang, S.,Xu, P.,Tan, Y.,You, C.,Zhang, Y.,Jiang, Y.,Xu, H.E. Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT 1F -G protein complex. Cell Res., 31:1036-1038, 2021 Cited by PubMed: 34239069DOI: 10.1038/s41422-021-00527-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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